GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs9815354 | 1 | rs6796210 | chr3:41851718 | ULK4 | chr3:41288091-42003660:- | 0.54 | 6.52 | 9.78E-10 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs6797165 | chr3:41887777 | ULK4 | chr3:41288091-42003660:- | 0.54 | 6.37 | 2.18E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs6800862 | chr3:134228628 | ANAPC13 | chr3:134196547-134204865:- | 0.38 | 4.37 | 2.26E-5 | Height |
| UCEC | cis | rs9815354 | 1 | rs6801343 | chr3:41767234 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.35 | 2.36E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs6801596 | chr3:134252114 | ANAPC13 | chr3:134196547-134204865:- | 0.38 | 4.37 | 2.26E-5 | Height |
| UCEC | cis | rs9815354 | 1 | rs6802340 | chr3:41894034 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.25 | 3.94E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs6802654 | chr3:134217072 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.64 | 7.4E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs6803560 | chr3:41824480 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.26 | 3.82E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs6803652 | chr3:41824556 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.26 | 3.82E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs6804770 | chr3:134230234 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.62 | 8.08E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs6805880 | chr3:41865397 | ULK4 | chr3:41288091-42003660:- | 0.45 | 5.13 | 8.63E-7 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs6806417 | chr3:134211446 | ANAPC13 | chr3:134196547-134204865:- | -0.4 | -4.62 | 8.15E-6 | Height |
| UCEC | cis | rs1577917 | 1 | rs68171315 | chr6:86707400 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -5.82 | 3.33E-8 | Response to antipsychotic treatment |
| UCEC | cis | rs6860540 | 1 | rs6860540 | chr5:156938327 | NIPAL4 | chr5:156887027-156901729:+ | -0.46 | -4.94 | 2.05E-6 | Inflammatory skin disease |
| UCEC | cis | rs568617 | 1 | rs687672 | chr11:65649984 | CTSW | chr11:65647284-65651212:+ | 0.51 | 8.41 | 2.71E-14 | Crohn's disease |